{"id":6878,"date":"2021-02-25T15:21:43","date_gmt":"2021-02-25T21:21:43","guid":{"rendered":"https:\/\/ibio.org\/?p=6878"},"modified":"2021-02-25T15:25:37","modified_gmt":"2021-02-25T21:25:37","slug":"national-rare-disease-day-recognizing-neurogenic-orthostatic-hypotension","status":"publish","type":"post","link":"https:\/\/ibio.org\/national-rare-disease-day-recognizing-neurogenic-orthostatic-hypotension\/","title":{"rendered":"National Rare Disease Day: Recognizing Neurogenic Orthostatic Hypotension"},"content":{"rendered":"

In the United States, a rare disease is defined as a condition that affects fewer than 200,000 people. Each\u00a0 year on February 28, the rare disease community joins together on Rare Disease Day to raise awareness of\u00a0 as many as 7,000 rare diseases affecting an estimated 25-30 million Americans. It is a day where the\u00a0 collective voices of patients and families impacted by rare diseases advocate for more research and better\u00a0 access to diagnosis and treatment. In observance of Rare Disease Day, Lundbeck looks to shine a\u00a0 spotlight on a rare condition called neurogenic orthostatic hypotension (nOH).\u00a0\u00a0<\/span><\/p>\n

What is nOH?\u00a0<\/i><\/b><\/p>\n

nOH is a condition that causes abnormally low blood pressure after standing in people with nervous\u00a0 system disorders. Because this condition cause damage to the nervous system, the body may not release\u00a0 enough of a chemical called norepinephrine, which helps to keep blood pressure from dropping too low.\u00a0 Without enough norepinephrine, blood pressure remains low after standing, which may result in\u00a0 symptoms like dizziness, lightheadedness, blurry vision, or fatigue.\u00a0\u00a0<\/span><\/p>\n

Who Experiences nOH?\u00a0\u00a0<\/i><\/b><\/p>\n

Those who are living with neurodegenerative conditions, like Parkinson\u2019s disease (PD), multiple system\u00a0 atrophy (MSA) and pure autonomic failure (PAF), can be at risk for this condition. Although considered rare, symptomatic nOH is estimated to affect 20% of patients who have PD, 80% of those living with\u00a0 MSA and nearly 100% of PAF patients.\u00a0<\/span><\/p>\n

Understanding the Symptoms of nOH.\u00a0\u00a0<\/i><\/b><\/p>\n

There are a variety of symptoms associated with nOH. Some of those are:<\/span><\/p>\n